This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Scopus Google Scholar Articles by Oliver, W. C. PubMed PubMed Citation Articles by Oliver, W. C. Pubmed/NCBI databases Medline Plus Health Information Blood Thinners Social Bookmarking                         What's this?

Anticoagulation and Coagulation Management for ECMO

Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota, oliver.william{at}mayo.edu

Advances in extracorporeal membrane oxygenation (ECMO) management have helped to reduce complications compared with its inception but they remain high. The principal causes of mortality and morbidity are bleeding and thrombosis. The nonbiologic surface of an extracorporeal circuit provokes a massive inflammatory response leading to consumption and activation of procoagulant and anticoagulant components. The vast differences in neonatal and adult anticoagulation and transfusion requirements demands tremendous clinical knowledge to provide the best care. Increased use of thrombelastogram will complement other methods currently being used to improved care. Methods to recognize the level of thrombin formation at the bedside could help reduce neurologic complications. ECMO requires a multidisciplinary team approach to achieve the best outcomes.

Key Words: anticoagulation • transfusion • extracorporeal circuit • thromboelastogram • thrombosis

Seminars in Cardiothoracic and Vascular Anesthesia, Vol. 13, No. 3, 154-175 (2009)
DOI: 10.1177/1089253209347384


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?