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Ischemic Mitral Regurgitation

Department of Anesthesiology, St. Luke's-Roosevelt Hospital Center, Columbia University, New York, NY

Daniel M. Thys, MD

Department of Anesthesiology, St. Luke's-Roosevelt Hospital Center, Columbia University, New York, NY; ThysD{at}chpnet.org

Ischemic mitral regurgitation is the regurgitation seen with structurally normal valve leaflets that occurs in approximately 20% of patients after myocardial infarction and 56% of patients with congestive heart failure caused by ischemic or nonischemic cardiomyopathy. The initiating event is an ischemic insult that results in remodeling of the left ventricle toward a more spherical shape and new wall motion abnormalities. These changes lead to annular dilation and subvalvular distortion that prevent the mitral leaflets from coapting and closing completely during the contraction phase. Treatment options include coronary revascularization, ring annuloplasty, valve repair and replacement, or left ventricle reconstruction by way of localized reshaping or resection. Pharmacotherapy, aimed at raising left ventricular pressure without increasing tethering or left ventricular volume, is included in the treatment options for improving ischemic mitral regurgitation.

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Seminars in Cardiothoracic and Vascular Anesthesia, Vol. 10, No. 1, 73-77 (2006)
DOI: 10.1177/108925320601000113


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This Article Abstract Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by (Cindy) Le, H. Articles by Thys, D. M. Search for Related Content PubMed PubMed Citation Articles by (Cindy) Le, H. Articles by Thys, D. M. Social Bookmarking                         What's this?