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Treatment of Perioperative Myocardial Ischemia

Department of Anesthesiology, Medical Center Boulevard, Winston-Salem, NC 27157-1009

Prevention and treatment of myocardial ischemia re mains a central focus of perioperative care. Myocardial ischemia is best understood in terms of myocardial oxygen supply and demand ratios. Conventional ther apy includes nitrates, β-blockers, and calcium channel blockers. In all 3 drug classes, ischemia is reduced by either improving supply, decreasing demand, or both. More recent investigation evaluates these medications either as prophylactic therapy or as a component of long-term risk reduction for cardiac morbid events. Newer therapies, including anticoagulation, pain ther apy, normothermia, central neuroaxial techniques, and other therapies, are reviewed.

Seminars in Cardiothoracic and Vascular Anesthesia, Vol. 5, No. 2, 166-183 (2001)
DOI: 10.1053/scva.2001.23719


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